Publications
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Independent Work
9. Iron Status Influences Mitochondrial Disease Progression in Complex I-Deficient Mice
Kelly, C.; Couch, R.K.; Ha, V.T.; Bodart, C.M.; Wu, J.; Huff, S.; Herrel, N.T.; Kim, H.D.; Zimmermann, A.O.; Shattuck, J.; Pan, Y.-C.; Kaeberlein, M.*; Grillo, A.S.* eLife 2023, 12, e75825.
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  • ​Co-Corresponding Authors
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​8. Acarbose Suppresses Symptoms of Mitochondrial Disease in a Mouse Model of Leigh Syndrome
Bitto, A.; Grillo, A.S., Ito, S.K.; Stanaway, I.; Nguyen, B.; Ying, K.; Tung, H.; Smith, K.; Tran, N.; Velikanje, G.; Urfer, S.; Snyder, J.; Barton, J.; Sharma, A.; Kayser, E.-B.; Wang, L.; Smith, D.; Thompson, J.W.; DuBois, L.; DePaolo, W.; Kaeberlein, M. Nat. Metab. 2023. 5, 955-967.
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Mentored Publications
7. The NDUFS4 Knockout Mouse: A Dual Threat Model of Childhood Mitochondrial Disease and Normative Aging
Grillo, A.S.; Bitto, A.; Kaeberlein, M.  Methods Mol. Biol. 2021, 2277, 143-155.
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  • Invited Book Chapter

6. PKC Downregulation upon Rapamycin Treatment Attenuates Mitochondrial Disease
Martin-Perez, M.*; Grillo, A.S.*; Ito, T.*; Valente, A.S.; Han, J.; Entwisle, S.; Huang, H.Z.; Kim, D.; Yajima, M.; Kaeberlein, M.; Villen, J.  Nat. Metab. 2020, 2, 1472-1481.
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  • * These authors contributed equally to this work

5. Small Molecule Ion Channel Restores Host Defenses in Cystic Fibrosis Airway Epithelia
Muraglia, K.A.; Chorghade, R.S.; Kim, B.R.; Tang, X.X.; Shah, V.S.; Grillo, A.S.; Daniels, P.N.; Cioffi, A.G.; Karp, P.H.; Zhu, L.; Welsh, M.J.; Burke, M.D.  Nature 2019, 567, 405-408.
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4. FAM210B is an Erythropoietin Target and Regulates Erythroid Heme Synthesis by Controlling Mitochondrial Iron Import and Ferrochelatase Activity
Yien, Y.Y.; Shi, J.; Chen, C.; Cheung, J.T.M.; Grillo, A.S.; Shrestha, R.; Li, L.; Zhang, X.; Kafina, M.D.; Kingsley, P.D.; King, M.J.; Ablain, J.; Li, H.; Zon, L.I.; Palis, J.; Burke, M.D.; Bauer, D.E.; Orkin, S.H.; Koehler, C.M.; Phillips, J.D.; Kaplan, J.; Ward, D.M.; Lodish, H.F.; Paw, B.H.  J. Biol. Chem. 2018, 293, 19797-19811.
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3. Restored Iron Transport by a Small Molecule Promotes Absorption and Hemoglobinization in Animals
Grillo, A.S.; SantaMaria, A.M.; Kafina, M.D.; Cioffi, A.G.; Huston, N.C.; Han, M.; Seo, Y.A.; Yien, Y.Y.; Nardone, C.; Menon, A.V.; Fan, J.; Svoboda, D.C.; Anderson, J.B.; Hong, J.D.; Nicolau, B.G.; Subedi, K.; Gewirth, A.A.; Wessling-Resnick, M.; Kim, J.; Paw, B.H.; Burke, M.D.  Science 2017, 356, 608-616.
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2. Restored Physiology in Protein-Deficient Yeast by a Small Molecule Channel
Cioffi, A.G.; Hou, J.; Grillo, A.S.; Diaz, K.A.; Burke, M.D.  J. Am. Chem. Soc. 2015, 137, 10096-10099.
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1. From Synthesis to Function via Iterative Assembly of N-Methyliminodiacetic Acid Boronate Building Blocks
Li, J.; Grillo, A.S.; Burke, M.D.  Acc. Chem. Res. 2015, 48, 2297-2307.
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  • Invited Review